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Sarah Constantin
sarahconstantin.substack.com · Personal blog · on HN since 2022
Sarah Constantin writes essays on AI, biotech, neuroscience, and data problems in industry.
What HN saysHN commenters point to her data integration piece to explain Palantir-style work, and to her posts on ultrasound neuromodulation as background on emerging technology.
26HN people shared it
4linked it in comments
31stories submitted
752story points
3 months agolast shared
2022people per year2026
Most-shared posts
- 1The Great Data Integration Schlep5 people · 5 points · first shared 2024 · discussion on HN
- 2What does the cerebellum do?2 people · 438 points · first shared 2023 · 206 comments on HN
- 3“Scaling Laws” for AI and Some Implications2 people · 2 points · first shared 2023 · discussion on HN
- 4I Am Not an AI Doomer2 people · 2 points · first shared 2023 · discussion on HN
- 5Why infinite coin flipping is bad2 people · 1 points · first shared 2023 · discussion on HN
- 6Old Spleens Suck (2021)1 people · 197 points · first shared 2022 · 84 comments on HN
- 7The Enchippening1 people · 75 points · first shared 2024 · 41 comments on HN
- 8Is Human Intelligence Simple?1 people · 3 points · first shared 2022 · discussion on HN
- 9Unblocking Abundance1 people · 3 points · first shared 2022 · discussion on HN
- 10What Really Happens When a Neuron Fires? (Part 1)1 people · 3 points · first shared 2024 · discussion on HN
- 11Multiplex Gene Editing: Where Are We Now?1 people · 2 points · first shared 2024 · discussion on HN
- 12Fun with CellxGene1 people · 2 points · first shared 2024 · discussion on HN
- 13LLM Applications I Want to See1 people · 2 points · first shared 2024 · discussion on HN
- 14Grid Scale Energy Storage Deployment by Technology Type1 people · 2 points · first shared 2022 · discussion on HN
- 15600+ Early-Stage Projects1 people · 2 points · first shared 2023 · discussion on HN
What HN people wrote when they linked it
FergusArgyll · 2025-08-04
This was an article that really helped me understand it
https://sarahconstantin.substack.com/p/the-great-data-integration-schl…
skybrian · 2024-11-09
Here are some in-depth blog posts from ex-employees:
https://sarahconstantin.substack.com/p/the-great-data-integration-schl…
https://nabeelqu.substack.com/p/reflections-on-palantir
SilasX · 2024-09-25
There were two things going on: A) Betting more aggressively than the Kelly Criterion, which indicates a bad understanding of how to reason about risk and EV[1], and, separately B) taking unnecessary, negative EV risks that have no justification beyond laziness.
B) include things like "having such sloppy accounting that you simply forget about major accounts[2] and are unintelligible to potential buyers" and "storing critical private keys in a text file that lots of people have poorly logged access to".
[1] lay explanation: https://sarahconstantin.substack.com/p/why-infinite-coin-flipping-is-b…
[2] the infamous "hidden, poorly labeled fiat account" for example
Sniffnoy · 2023-11-29
Sarah Constantin has been writing a series of posts about such technology (these aren't the only people trying it) over on her blog:
* https://sarahconstantin.substack.com/p/ultrasound-neuromodulation
* https://sarahconstantin.substack.com/p/how-ultrasound-neuromodulation-…
* https://sarahconstantin.substack.com/p/transcranial-ultrasound-neuromo…
* https://sarahconstantin.substack.com/p/why-should-neuroenhancement-be-…
* https://sarahconstantin.substack.com/p/whos-working-on-ultrasound-neur…