Boolean Biotech
blog.booleanbiotech.com · Personal blog · on HN since 2016
Boolean Biotech is a blog on bioinformatics and biotech, covering home DNA sequencing, protein engineering, antibody design and cloud lab tools.
What HN saysHN links it for its home DNA sequencing guides and for results of a protein binder design competition. Commenters call those results cool.
17HN people shared it
2linked it in comments
16stories submitted
266story points
10 months agolast shared
2016people per year2026
Most-shared posts
- 1Engineering Proteins in the Cloud with Python and Transcriptic7 people · 29 points · first shared 2016 · discussion on HN
- 2DNA Sequencing at Home with the Flongle3 people · 4 points · first shared 2021 · discussion on HN
- 3How to sequence your genome at home1 people · 184 points · first shared 2021 · 45 comments on HN
- 4Oral microbiome sequencing after taking probiotics1 people · 30 points · first shared 2026 · 6 comments on HN
- 5Engineering Proteins in the Cloud with Python and Transcriptic for $3601 people · 11 points · first shared 2016 · discussion on HN
- 6AI Antibody Design in 20251 people · 4 points · first shared 2025 · 1 comments on HN
- 7Instagram celebrity generation using neural nets: Jake Dangerback1 people · 2 points · first shared 2019 · discussion on HN
- 8Tools for Working on the Cloud1 people · 1 points · first shared 2019 · discussion on HN
- 9The Adaptyv binder design competition (2024)1 people · 1 points · first shared 2026 · discussion on HN
- 10Adaptyv binder design competition1 people · first shared 2024
What HN people wrote when they linked it
igorkraw · 2024-09-23
Full disclosure: my employers competition, but I think the results are cool.
Added "results" to the title to be clearer that this is not ongoing, hope that level of editorializing is okay, I tried to match the "blandness" level.
Context here: https://design.adaptyvbio.com/
And some cool writeups and discussion around the competitoin here:
- http://blog.booleanbiotech.com/adaptyv-binder-design-competition.html
- https://x.com/pranamanam/status/1837702358995812754?s=19
up6w6 · 2021-12-27
Reports of people trying to use it at home without any special lab:
https://abarry.org/dna-sequencing-in-our-extra-bedroom/
http://blog.booleanbiotech.com/sequencing-at-home-with-flongle.html